The pattern of steroid synthesis in the placenta is complicated by the fact that the placenta is an ‘incomplete endocrine gland’: it lacks the key enzymes required to synthesise the full range of steroid hormones. Most notably, the placenta does not express the CYP17A enzyme necessary to convert progestogens to androgens. As a consequence, for the placenta to synthesise estrogens, it has to work in concert with the fetal adrenal gland and maternal liver, with steroids passing back and forth between the placenta, fetal and maternal circulations. Importantly, 16 α -hydroxyandrostenedione secreted from the fetal zone of the fetal adrenal cortex can, in the placenta, be aromatised to estriol, a unique steroid that is synthesised only by the placenta and that can be used as a surrogate marker to assess the functional status of the fetal adrenal gland.
There is much experimental evidence from in vitro studies and animal studies that Cordyceps sinensis an inhibitory effect on the onset and progression of cancer, especially polysaccharides in Cordyceps have a strong anti-cancer activity, partly by strong activation of the immune. * Also sterols and adenosine in Cordyceps have antitumor activity. The medicinal mushroom in countries like Japan, Korea and China by cancer chemotherapy or radiation in addition to frequently used for side effects of conventional treatments such as immunosuppression and the combat effectiveness of cancer therapy to increase.