Anabolic, anti-catabolic, anti-proteolytic, protein-sparing... These are terms that describe the state of protein affairs in muscle. The bodybuilding community likes to define anabolic compounds as those which increase amino acid shuttling into muscle and increase protein synthesis. Likewise, anti-catabolic, or antiproteolytic (the more specifically correct term) compounds are defined as those which decrease amino acid shuttling out of muscle (also called protein-sparing). Irrespective of whether amino acids are being gained within muscle due to an increase in the influx of amino acids and enhanced protein synthesis, or due to the conservation of amino acids already within the muscle, or both, the resulting intramuscular environment is anabolic. This is a really good thing for bodybuilders.
Ajuga turkestanica and myostatin A study on the anabolic effects of Ajuga turkestanica was published in 2012 in Chinese Medicine. Researchers were working for PoliNat, a Spanish company that sells plant-based bioactive extracts – including an extract from Ajuga turkestanica. The researchers observed that at a concentration of 1 micromole Ajuga turkestanica ecdysteroids the muscle cells started to make less myostatin. The researchers repeated the experiment and exposed the muscle cells this time to 1 micromole methandienone – a powerful anabolic. And, lo and behold – the ecdysteroids turned out to be more effect myostatin inhibitors than the anabolic.
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