All corneal infections should be followed daily until there is a marked improvement. Since fungal infections run a protracted course, their follow up is longer and after a few days the interval between evaluations increases according to its progress. Complete healing might take weeks and even months. The intraocular pressure should be closed monitored during the episode. It should be noted that epithelialization does not necessary means that the ulcer is healing. In fact it might hinder the penetration of the fungicide. Confocal microscopy might be an effective additional method to follow the success or failure of the therapy. It does so by direct examination of the organism, inflammation, and corneal stromal cells.